博士,教授,博士生导师
教育经历
工学博士,2006.09~2009.12,南京工业大学(制药工程专业)
医学硕士,2000.09~2003.06,江苏大学(生药学专业)
工学学士,1996.09~2000.06,安徽农业大学(农产品贮藏与加工专业)
工作经历
2017.07~,51吃瓜网,教授
2016.08~2017.02,德国格赖夫斯瓦尔德大学访问学者(国家留学基金)
2011.08~2012.08,美国华盛顿州立大学访问学者(省政府留学奖学金)
2011.08~2017.07,51吃瓜网,副教授
2011.07~2014.12,江苏大学,博士后
2006.04~2011.08,51吃瓜网,讲师
2003.05~2006.04,51吃瓜网,助教
研究领域
(1)生物催化与转化
(2)蚕桑资源利用
(3)桑树病虫害防控
主要讲授课程
(1)生物分离工程、生物资源开发与利用、生物分离工程实验、天然药物化学等(本科生)
(2)生物催化与转化、生物基产品工程、蚕桑资源生物转化、生物转化与合成生物学、农业资源利用新技术等(研究生)
(3)Biotransformation of Sericulture Resource(留学生)
主要学术和社会兼职
(1)《Frontiers in Nutrition》Associate Editor,《Scientific Reports》Editorial Board Member,《Sustainability》Editorial Board Member,《Frontiers in Bioengineering and Biotechnology》Review Editor,《中国蚕业》编委,《51吃瓜网学报》(自然科学版)编委
(2)中国蚕学会第十一届理事会理事、资源开发专业委员会副主任委员、教育与科普工作委员会副主任委员,中国昆虫学会第十一届理事会昆虫产业化专业委员会委员
(3)江苏省农学会休闲昆虫分会第一届副理事长,江苏省生物化学与分子生物学学会第十一届常务理事、第十届监事,江苏省高校生物学学科联盟常务理事,江苏省蚕桑学会第十二届理事会理事,江苏省化工学会第十一届理事会理事
(4)江苏省农学类研究生教育指导委员会委员
(5)法国国家研究总署项目(French National Research Agency, ANR)、荷兰国家科研基金(Netherlands Organisation for Scientific Research, NWO)、国家自然科学基金等项目评审专家
代表性论著
[1] Jin-Zheng Wang†, Cheng-Kun Wu†, Xin-Ying Wang, Yuan-Zhi Xu, Richard Ansah Herman, Sheng Sheng, Shuai You, Jun Wang*, Fu-An Wu. One positive part of copper ion on biocatalysts: CNPs@Cu-Trypsin-assisted aqueous extraction technique for simultaneous exploration edible insect oil and protein. Chemical Engineering Journal. 2023, 464: 142560.
[2] Richard Ansah Herman, Ellen Ayepa, Wen-Xin Zhang, Zong-Nan Li, Xuan Zhu, Michael Ackah, Shuang-Shuang Yuan, Shuai You, Jun Wang*. Molecular modification and biotechnological applications of microbial aspartic proteases. Critical Reviews in Biotechnology. 2023, DOI:10.1080/07388551.2023.2171850
[3] Yi-Jiangcheng Li, Tian-Le Hong, Hong-Chao Chen, Feng-Ming Gu, Zhi-Xiang Liu, Shuai You, Fu-An Wu, Sheng Sheng*, Jun Wang*. Odorant-binding protein 6 contributes high binding affinity to insecticides in a parasitic wasp Meteorus pulchricornis (Hymenoptera: Braconidae). Journal of Agricultural and Food Chemistry. 2023, 71(11): 4498-4509.
[4] Zhi-Yuan Bai, Shuai You, Fang Zhang, Zhi-Wei Dong, Yi-Fan Zhao, Hong-Jian Wen, Jun Wang*. Efficient fermentable sugar production from mulberry branch based on a rational design of GH10 xylanase with improved thermal stability. Renewable Energy. 2023, 206: 566-573.
[5] Shuai You†, Lin-Lin Zhu†, Shu-Meng Zhang, Richard-Ansah Herman, Yang Li, Li-Tian Geng, Huan Chen, Fu-An Wu, Jun Wang*. Recyclable and efficient isoquercitrin production with whole-cell catalysis of improved GH78 α-L-rhamnosidase by domain truncation strategy. Industrial Crops and Products. 2023, 191: 115945.
[6] Yi-Tong Li, Ting Huang, Jin-Zheng Wang, Cheng-Hai Yan, Lu-Chan Gong, Fu-An Wu, Jun Wang*. Efficient acquisition of high-purity cyanidin-3-O-glucoside from mulberry fruits: An integrated process of ATPS whole-cell transformation and semi-preparative HPLC purification. Food Chemistry. 2023, 404: 134651.
[7] Richard Ansah Herman, Cheng-Hai Yan, Jin-Zheng Wang, Xiao-Meng Xun, Cheng-Kun Wu, Zong-Nan Li, Ellen Ayepa, Shuai You, Lu-Chan Gong, Jun Wang*. Insight into the silkworm pupae: Modification technologies and functionality of the protein and lipids. Trends in Food Science & Technology. 2022, 129: 408-420.
[8] Shuai You, Yi-Xin Zhang, Fan Shi, Wen-Xin Zhang, Jing Li , Sheng Zhang, Zhong-Li Chen, Wei-Guo Zhao, Jun Wang*. Lowering energy consumption for fermentable sugar production from Ramulus mori: engineered xylanase synergy and improved pretreatment strategy. Bioresource Technology. 2022, 344: 126368.
[9] Yan Hu, Can-Yang Shi, Xiao-Meng Xun, Ya-Li Chai, Shuai You, Fu-An Wu, Jun Wang*. W/W droplet-based microfluidic interfacial catalysis of xylanase-polymer conjugates for xylooligosaccharides production. Chemical Engineering Science. 2022, 248: 117110.
[10] Yu-Rong Bian, Wen-Jing Li, Lian-Han Pan, Qiang-Min Peng, Shuai You, Sheng Sheng, Jun Wang*, Fu-An Wu. Sweet-flavored peptides with biological activities from mulberry seed protein treated by multifrequency countercurrent ultrasonic technology. Food Chemistry. 2022, 367: 130647.
[11] Yi-Jiangcheng Li, Hong-Chao Chen, Xin-Hao Liang, Shan-Shan Wang, Han-Qi Zhu, Meng-Wen Yan, Fu-An Wu, Jun Wang*, Sheng Sheng*. Identification of candidate chemosensory genes by antennal transcriptome analysis in an ectoparasitoid wasp. Journal of Applied Entomology. 2022, 146(3): 335-351.
[12] Shuai You, Jing Li, Fang Zhang, Zhi-Yuan Bai, Saidi Shittu, Richard-Ansah Herman, Wen-Xin Zhang, Jun Wang*. Loop engineering of a thermostable GH10 xylanase to improve low-temperature catalytic performance for better synergistic biomass-degrading abilities. Bioresource Technology. 2021, 342: 125962.
[13] Shuai You, Zi-Qian Zha, Jing Li, Wen-Xin Zhang, Zhi-Yuan Bai, Yang-Hao Hu, Xue Wang, Yi-Wen Chen, Zhong-Li Chen, Jun Wang*, Hui-Ying Luo*. Improvement of XYL10C_∆N catalytic performance through loop engineering for lignocellulosic biomass utilization in feed and fuel industries. Biotechnology for Biofuels. 2021, 14:195.
[14] Jin-Zheng Wang, Cheng-Kun Wu, Chen-Hai Yan, Huan Chen, Shuai You, Sheng Sheng, Fu-An Wu, Jun Wang*.Nutritional targeting modification of silkworm pupae oil catalyzed by a smart hydrogel immobilized lipase. Food & Function, 2021, 12: 6240-6253.
[15] Cheng-Hai Yan, Xiao-Meng Xun, Jiao Wang, Jin-Zheng Wang, Shuai You, Fu-An Wu, Jun Wang*. An alternative solution for α-linolenic acid supplements: In vitro digestive properties of silkworm pupae oil in a pH-stat system. Food & Function, 2021, 12: 2428-2441.
[16] Fan Zhang, Shuai You, Ting Huang, Jin-Zheng Wang, Lin-Lin Zhu, Bo Wang, Wang-Sheng Ye, Richard Ansah Herman, Heng Luo, Jun Wang*. Dual promoter strategy enhances co-expression of α-L-rhamnosidase and enhanced fluorescent protein for whole-cell catalysis and bioresource valorization. Science of the Total Environment. 2020, 722: 137865.
[17] Shuai You, Chen Xie, Rui Ma, Huo-Qing Huang, Richard Ansah Herman, Xiao-Yun Su, Yan Ge, Hui-Yi Cai, Bin Yao, Jun Wang*, Hui-Ying Luo*. Improvement in catalytic activity and thermostability of a GH10 xylanase and its synergistic degradation of biomass with cellulase. Biotechnology for Biofuels. 2019, 12, 278.
[18] Chang-Tong Zhu, Yi-Yuan Mei, Lin-Lin Zhu, Yan Xu, Sheng Sheng, Jun Wang*. Recombinant Escherichia coli BL21-pET28a-egfp cultivated with nanomaterials in a modified microchannel for biofilm formation. International Journal of Molecular Sciences. 2018, 19(9), 2590.
[19]Fang-Qin Wang, Shu He, Chang-Tong Zhu, Ulrich Rabausch, Wolfgang Streit, Jun Wang*. The combine use of continuous-flow microchannel reactor and ionic liquid cosolvent for efficient biocatalysis of unpurified recombinant enzyme. Journal of Chemical Technology and Biotechnology. 2018, 93(9): 2671-2680.
[20] Xin-Yi Shi, Tai-Ying Li, Min Wang, Wei-Wei Wu, Wen-Jing Li, Qiong-Ying Wu, Fu-An Wu, Jun Wang*. Converting defatted silkworm pupae by Yarrowia lipolytica for enhanced lipid production. European Journal of Lipid Science and Technology. 2017, 119, 1600120.
[21] An Gong†, Chang-Tong Zhu†, Yan Xu, Fang-Qin Wang, D’assise Kinfack Tsabing, Fu-An Wu, Jun Wang*. Moving and unsinkable graphene sheets immobilized enzyme for microfluidic biocatalysis. Scientific Reports. 2017, 7: 4309.
[22] Jun Wang*, Xi Liu, Xu-Dong Wang, Tao Dong, Xing-Yu Zhao, Dan Zhu, Yi-Yuan Mei, Guo-Hua Wu. Selective synthesis of human milk fat-style structured triglycerides from microalgal oil in a microfluidic reactor packed with immobilized lipase. Bioresource Technology. 2016, 220: 132-141.
[23] Cai-Feng Yang, Yu Zhou, Yu Zheng, Chang-Long Li, Sheng Sheng, Jun Wang*, Fu-An Wu*. Enzymatic modification of chitosan by cinnamic acids: Antibacterial activity against Ralstonia solanacearum. International Journal of Biological Macromolecules. 2016, 87: 577-585.
[24] Jun Wang, Xu-Dong Wang, Xing-Yu Zhao, Xi Liu, Tao Dong, Fu-An Wu. From microalgae oil to produce novel structured triacylglycerols enriched with unsaturated fatty acids. Bioresource Technology. 2015, 184: 405-414.
[25] An Gong†, Shuang-Shuang Gu†, Jun Wang*, Sheng Sheng, Fu-An Wu. A peculiar segmented flow microfluidics for isoquercitrin biosynthesis based on coupling of reaction and separation. Bioresource Technology. 2015, 193: 498-506.
[26] Jun Wang, Shuang-Shuang Gu, Hong-Sheng Cui, Xiang-Yang Wu, Fu-An Wu. A novel continuous flow biosynthesis of caffeic acid phenethyl ester from alkyl caffeate and phenethanol in a packed bed microreactor. Bioresource Technology. 2014, 158: 39-47.
[27] Shuang-Shuang Gu, Jun Wang*, Xian-Bin Wei, Hong-Sheng Cui, Xiang-Yang Wu, Fu-An Wu. Enhancement of lipase-catalyzed synthesis of caffeic acid phenethyl ester in ionic liquid with DMSO co-solvent. Chinese Journal of Chemical Engineering. 2014, 22: 1314-1321.
[28] Na Pang†, Shuang-Shuang Gu†, Jun Wang*, Hong-Sheng Cui, Fang-Qin Wang, Xi Liu, Xing-Yu Zhao, Fu-An Wu. A novel chemoenzymatic synthesis of propyl caffeate using lipase-catalyzed transesterification in ionic liquid. Bioresource Technology. 2013, 139: 337-342.
[29] Jun Wang, Guo-Xia Sun, Liang Yu, Fu-An Wu, Xi-Jie Guo. Enhancement of the selective enzymatic biotransformation of rutin to isoquercitrin using an ionic liquid as a co-solvent. Bioresource Technology. 2013, 128: 156-163.
[30] Jun Wang, Ding-Qiang Lu, Qiu-Jun Sun, Hui Zhao, Xiu-Quan Ling, Ping-Kai Ouyang. Reactive extraction and recovery of mono-caffeoylquinic acids from tobacco wastes by trialkylphosphine oxide. Chemical Engineering Science. 2012, 78: 53-62.
* Corresponding author, †Joint first authors.
代表性授权专利
[1] 王俊, 王鹏源, 涂清波, 盛晟, 吴福安. 莰烯酯类衍生物的应用. 国家发明专利, 授权证书: ZL 202011455932.7, 授权公告日: 2022.03.11.
[2] 王俊, 朱长通, 梅艺苑, 许晏, 盛晟, 吴福安. 一种微通道内纳米材料混合液分段流培养生物被膜的方法. 国家发明专利, 授权证书: ZL 201710770550.5, 授权公告日: 2019.12.17.
[3] 王俊, 王方芹, 何姝, 李文静, 吴福安. 重组α-L-鼠李糖苷酶粗提液用于微通道反应器中催化定向水解黄酮苷的方法. 国家发明专利, 授权证书: ZL 201610723949.3, 授权公告日: 2019.09.27.
[4] 王俊, 王旭东, 庞娜, 王超, 吴福安. 基于酶促酸解棕榈酸甘油三酯合成结构脂质的方法. 国家发明专利证书: ZL 201410407944.0, 授权公告日: 2016.09.14.
[5] 王俊, 顾双双, 崔红生, 魏贤彬, 吴福安. 三明治型微反应器及其在酶促合成咖啡酸苯乙酯中的应用. 国家发明专利证书: ZL 201310358449.0, 授权公告日: 2016.04.20.
[6] 王俊, 顾双双, 崔红生, 吴福安. 两相体系中酶促合成异槲皮苷的分段流微反应工艺. 国家发明专利证书: ZL 201310694293.3, 授权公告日: 2015.07.08.
[7] 王俊, 王旭东, 刘曦, 赵星宇, 吴福安. 一种脂肪酶促酸解藻油制备母乳脂肪替代品的方法. 国家发明专利证书: ZL 201310694776.3, 授权公告日: 2015.06.17.
[8] 王俊, 吴福安, 张金亮. 一种基于可逆反应的组合络合分离蚕蛹油中不饱和脂肪酸的方法. 国家发明专利证书: ZL 201110343010.1, 授权公告日: 2013.10.30.
[9] 王俊, 吴福安, 谢谢, 方水琴, 张研, 吕荣宾. 一株黑曲霉菌株及其在富集提取桑白皮中1-脱氧野尻霉素的应用. 国家发明专利证书: ZL 201110168168.X, 授权公告日: 2013.04.24.
[10] 王俊, 吴福安, 孙国霞, 王凯旋, 张磊霞, 郭锡杰. 一种桑红茶型速溶茶的制备方法. 国家发明专利证书: ZL 201110203340.0, 授权公告日: 2012.12.19.
[11]王俊, 吴福安, 王蒙, 张妍, 谢谢. 蜗牛酶在定向水解芦丁生物合成槲皮素中的应用. 国家发明专利证书: ZL 201010178064.2, 授权公告日: 2012.10.24. (已转让)
[12]王俊, 吴福安, 王蒙, 孙国霞, 卫哲. 酶促转化桑叶黄酮制备桑叶饮料的方法. 国家发明专利证书: ZL 201110167768.4, 授权公告日: 2012.10.24. (已转让)
荣誉与获奖
(1)江苏省高校优秀科技创新团队负责人(2023)
(2)团中央“挑战杯”竞赛指导暨科技创新宣讲团成员(2021)
(3)江苏省高校“青蓝工程”优秀教学团队负责人(2019)
(4)感动江苏教育人物——2018最美高校教师提名奖(2018)
(5)江苏省第五期“333工程”第三层次培养对象(2018)
(6)镇江市第十二届十大杰出青年(2018)
(7)Outstanding Contribution in Reviewing Award(2017)
(8)江苏省“六大人才高峰”高层次人才培养对象(2015)
(9)校“深蓝人才”青年学者第一层次培养对象(2015)
(10)江苏省高校“青蓝工程”中青年学术带头人(2014)
(11)江苏省高校优秀共产党员(2014)
(12)江苏省高校“青蓝工程”优秀青年骨干教师(2010)
(13)江苏省大中学生社会实践活动优秀指导教师(2005)
(14)中国产学研合作创新成果奖优秀奖(2019,1/7),江苏省科学技术奖三等奖(2019,3/10)
(15)江苏省教学成果(高等教育类)奖一等奖(2017,3/10)、二等奖(2013,3/7),江苏省研究生教育改革成果奖二等奖2项(2017,3/10;2019,10/10)
(16)指导学生参加“挑战杯”课外学术科技作品竞赛获第十七届全国一等奖、第十二届全国一等奖、第十四届全国二等奖、第十三届全国三等奖、第十一届全国三等奖、第十七届江苏省特等奖、第十四届江苏省二等奖和第十三届江苏省二等奖;指导学生参加“挑战杯”创业计划竞赛获第八届全国金奖、第七届全国银奖、第十二届全国铜奖、第十二届江苏省金奖、第六届江苏省特等奖和第七届江苏省银奖
(17)指导大学生科技作品获全国大学生生命科学创新创业大赛一等奖、全国大学生蚕桑生物技术创新大赛特等奖等奖项30余项
(18)指导研究生获国家奖学金10余人,完成江苏省研究生科技创新计划10余项,获江苏省优秀硕士学位论文2篇、校优秀硕士学位论文10余篇;指导本科生完成大学生实践创新训练计划项目国家级省级项目10余项,本科生毕业论文获江苏省普通高等学校本专科优秀毕业设计(论文)一等奖2项、二等奖6项、优秀团队3个
近期研究项目
(1)多相微流控异肽键介导表面展示酶的三维有序生物被膜串联催化机理(22278196,2023.01-2026.12),国家自然科学基金面上项目,主持人
(2)W/W液滴微流控糖苷酶-聚合物偶联体稳定皮克林界面的催化机理(21978121,2020.01-2023.12),国家自然科学基金面上项目,主持人
(3)分段式微流控生物被膜催化天然产物糖基定向改造研究(21676130,2017.01-2020.12),国家自然科学基金面上项目,主持人
(4)分段式微流控非水相酶促合成二咖啡酰奎尼酸的催化机理(21206061,2013.01-2015.12),国家自然科学基金青年项目,主持人
(5)面向蚕桑全产业链的多学科交叉融合新农科人才培养模式研究(2020.06-2023.06),教育部新农科研究与改革实践项目,主持人
(6)桑树柞树虫害防控(CARS-18-ZJ0305,2016.01-2020.12),国家蚕桑产业技术体系,团队骨干(3/5)
(7)桑树病虫害防控(CARS-22,2011.01-2015.12),国家蚕桑产业技术体系,团队骨干(2/6)
(8)微流场酶法加工蚕蛹精准制造活性肽和结构脂关键技术(BE2019358,2019.07-2022.06),江苏省重点研发计划(现代农业)项目,主持人
(9)休闲蚕桑产业药食两用资源挖掘与综合利用关键技术创新及示范(CX(20)2029,2020.08-2023.07),江苏省农业科技自主创新资金关键技术创新项目,主持人
(10)基于微藻转化废蚕蛹的酶催化定向合成新型母乳脂肪替代品关键技术研究(BE2013405,2013.07-2016.06),江苏省科技支撑计划(农业)项目,主持人
(11)低温微波辐射协同微流控酶催化定向合成异槲皮苷的机理(2013T60505,2013.01-2014.12),中国博士后科学基金特别资助项目,主持人
(12)微流控立体选择性生物合成二咖啡酰奎尼酸的催化机理(2012M510124,2012.01-2013.12),中国博士后科学基金面上项目(一等),主持人
(13)生物合成咖啡酸苯乙酯的分子催化机理及其反应分离耦合过程调控机制(BK2009213,2010.01-2012.12),江苏省自然科学基金面上项目,主持人
(14)新型植物诱抗剂冠菌素高产菌株选育及其用于绿色防控关键技术研究(BE2012365,2012.01-2015.06),江苏省科技支撑计划(农业)项目,副主持
(15)桑疫病致病机理的研究与生物防治产品开发(2013.01-2013.12),国家茧丝绸发展专项资金项目,副主持
(16)助力蚕桑产业精准扶贫的农业硕士校所政企协同培养模式研究(2019-NYZD-05,2019.11-2021.11),全国农业专业学位研究生教育指导委员会研究生教育管理重点课题,主持人
(17)面向蚕桑行业的理工农学专业研究生协同创新能力提升研究(JGZZ16_061, 2016.07-2018.06),江苏省研究生教育教学改革研究与实践课题重点项目,主持人
(2023年8月更新)
联系方式
江苏省镇江市丹徒区51吃瓜网长山校区212100
E-mail:wangjun@just.edu.cn; wangjunjs@126.com